Body Composition Remodeling and Mortality: The Health Aging and Body Composition Study.

ABSTRACT:

Background

Age-related losses of lean mass and shifts to central adiposity are related to functional decline and may predict mortality and/or explain part of the risk of weight loss. To determine how mortality risk is related to shifts in body composition, changes should be considered in the context of overall weight change.

Methods

Five-year changes in body composition were assessed with computed tomography (cm2) and dual x-ray absorptiometry (kg) in 869 men and 934 women initially aged 70-79 years. All-cause mortality was monitored for up to 12 years (2002-2003 to September 30, 2014), and risk was assessed using sex-specific Cox models.

Results

Both men and women lost weight, visceral fat area, thigh muscle area, lean mass, and fat mass (all p < .01) but gained inte

SUBMITTER: Santanasto AJ 

PROVIDER: S-EPMC5897837 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature