Influence of maternal and own genotype at tanning dependence-related SNPs on sun exposure in childhood.

ABSTRACT:

Background

Research suggests there may be a genetic influence on the likelihood of becoming tanning dependent (TD). The way in which mothers regulate their children's sun exposure may be affected by being TD. We investigated the associations between single nucleotide polymorphisms (SNPs) related to being TD and early sun exposure.

Methods

Data from the Avon Longitudinal Study of Parents and Children (ALSPAC) were used. Associations between 17 TD related SNPs in children and their mothers and 10 sun exposure variables in children (assessed via questionnaire at age 8) were analyzed in logistic and ordinal logistic regressions. Analyses were adjusted for principal components of population structure and age (at time of questionnaire response). Models with additional adjustment f

SUBMITTER: Khouja J 

PROVIDER: S-EPMC5898059 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature