Hip fracture incidence and mortality in chronic kidney disease: the GLOMMS-II record linkage cohort study.

ABSTRACT:

Background

Individuals on renal replacement therapy (RRT) have increased fracture risk, but risk in less advanced chronic kidney disease (CKD) is unclear.

Objective

To investigate CKD associations with hip fracture incidence and mortality.

Design

Record linkage cohort study Grampian Laboratory Outcomes Mortality and Morbidity Study II.

Setting

Single health region in Scotland.

Participants

All individuals (≥15 years) with sustained CKD stages 3-5 and those on RRT, and a 20% random sample of those with normal renal function, in the resident population in 2003.

Outcome measures

Outcomes were (1) incident hip fracture measured with (A) admissions or (B) deaths, with at least 5.5 years follow-up and (2) post-hip fracture mortality. Unadjusted and adju

SUBMITTER: Robertson L 

PROVIDER: S-EPMC5898333 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature