Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution.

ABSTRACT: In this paper, an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing. The samples are illuminated by a nearly coherent illumination system, where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor. To increase the resolution, a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene, with small planar displacements. Displacements are resolved by a hybrid approach: (i) alignment of the LR images by a fast feature-based registration method, and (ii) fine adjustment of the sub-pixel information using a continuous optim

SUBMITTER: Sobieranski AC 

PROVIDER: S-EPMC5898403 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature