Serious adverse events of older adults in nursing home and community intervention trials.

ABSTRACT:

Background/aims

Clinical trials of older adults are increasingly common, but risks of serious adverse events (SAE) may vary. We describe the incidence of SAE in two randomized trials, one community-based and one nursing home-based.

Methods

We performed a secondary data analysis from two randomized clinical trials at one academic health center and 21 nursing homes involving 200 sedentary community dwellers aged 70-89 years and 185 female nursing home residents aged 65 years or older. Interventions included structured physical activity to reduce mobility disability in the Lifestyle Interventions and Independence for Elders (LIFE) study and oral cranberry capsules to reduce bacteriuria plus pyuria in nursing home residents (CRANNY) trial. We measured SAE incidence per 100 perso

SUBMITTER: Datta R 

PROVIDER: S-EPMC5898490 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature