A new paradigm evaluating cost per cure of HCV infection in the UK.

ABSTRACT:

Background

New interferon (IFN)-free treatments for hepatitis C are more effective, safer but more expensive than current IFN-based therapies. Comparative data of these, versus current first generation protease inhibitors (PI) with regard to costs and treatment outcomes are needed. We investigated the real-world effectiveness, safety and cost per cure of 1st generation PI-based therapies in the UK.

Methods

Medical records review of patients within the HCV Research UK database. Patients had received treatment with telaprevir or boceprevir and pegylated interferon and ribavirin (PR). Data on treatment outcome, healthcare utilisation and adverse events (AEs) requiring intervention were collected and analysed overall and by subgroups. Costs of visits, tests, therapies, adverse e

SUBMITTER: Barclay ST 

PROVIDER: S-EPMC5898515 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature