Characteristics of cancer patients participating in presurgical lifestyle intervention trials exploring effects on tumor biology.

ABSTRACT:

Background

Poor diet and insufficient physical activity are strongly associated with an increased risk of several cancers. Preclinical studies suggest that lifestyle modifications may exert favorable effects on tumor biology. Randomized controlled trials in the presurgical setting serve as an ideal means to translate this research to humans; however, little is known about the characteristics of patients who enroll in these presurgical trials versus those who do not.

Methods

Screening databases from three presurgical lifestyle intervention trials for breast and prostate cancer patients conducted at Duke University Medical Center (NCT00049309) and the University of Alabama at Birmingham (NCT02224807 and NCT01886677) were combined for analysis. Demographic and anthropometric di

SUBMITTER: Dasher JA 

PROVIDER: S-EPMC5898572 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature