Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial.

ABSTRACT:

Background

Limited evidence suggests that physical activity may prevent frailty and associated negative outcomes in older adults. Definitive data from large long-term randomized trials are lacking.

Objective

To determine whether a long-term, structured, moderate-intensity physical activity program is associated with a lower risk for frailty and whether frailty status alters the effect of physical activity on the reduction in major mobility disability (MMD) risk.

Design

Multicenter, single-blind, randomized trial.

Setting

8 centers in the United States.

Participants

1635 community-dwelling adults, aged 70 to 89 years, with functional limitations.

Intervention

A structured, moderate-intensity physical activity program incorporating aerobic, resistan

SUBMITTER: Trombetti A 

PROVIDER: S-EPMC5898617 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature