Preference phenotypes to facilitate shared decision-making in rheumatoid arthritis.

ABSTRACT:

Objective

Implementing treat-to-target (TTT) strategies requires that patients with rheumatoid arthritis (RA) and their rheumatologists decide on how best to escalate care when indicated. The objective of this study was to develop preference phenotypes to facilitate shared decision-making at the point of care for patients failing methotrexate monotherapy.

Methods

We developed a conjoint analysis survey to measure the preferences of patient with RA for triple therapy, biologics and Janus kinase (JAK) inhibitors. The survey included seven attributes: administration, onset, bothersome side effects, serious infection, very rare side effects, amount of information and cost. Each choice set (n=12) included three hypothetical profiles. Preference phenotypes were identified by apply

SUBMITTER: Fraenkel L 

PROVIDER: S-EPMC5898982 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature