TESTOSTERONE SUPPLEMENTATION AND RETINAL VASCULAR DISEASE.

ABSTRACT:

Purpose

To determine whether testosterone supplementation is associated with retinal artery occlusion (RAO) or retinal vein occlusion (RVO).

Methods

Retrospective matched cohort study using data from a large national U.S. insurance database. The testosterone cohort consisted of all male patients who filled a prescription for testosterone from 2000 to 2013. Five controls were matched on age (±3 years), sex, race, and similar time in plan (±3 months) for every exposed patient. Exclusion occurred for <2 years in the plan, <1 eye care visit, medications known to affect androgen levels, and systemic diseases associated with occlusions or increased testosterone. Cox proportional hazard regression assessed the hazard of a new diagnosis of RAO or RVO while controlling for age, race,

SUBMITTER: Dedania VS 

PROVIDER: S-EPMC5899058 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature