Engineering nanoreactors using bacterial microcompartment architectures.

ABSTRACT: Bacterial microcompartments (BMCs) are organelles that encapsulate enzymes involved in CO2 fixation or carbon catabolism in a selectively permeable protein shell. Here, we highlight recent advances in the bioengineering of these protein-based nanoreactors in heterologous systems, including transfer and expression of BMC gene clusters, the production of template empty shells, and the encapsulation of non-native enzymes.

SUBMITTER: Plegaria JS 

PROVIDER: S-EPMC5899066 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature