Nonmonotonic spatial structure of interneuronal correlations in prefrontal microcircuits.

ABSTRACT: Correlated fluctuations of single neuron discharges, on a mesoscopic scale, decrease as a function of lateral distance in early sensory cortices, reflecting a rapid spatial decay of lateral connection probability and excitation. However, spatial periodicities in horizontal connectivity and associational input as well as an enhanced probability of lateral excitatory connections in the association cortex could theoretically result in nonmonotonic correlation structures. Here, we show such a spatially nonmonotonic correlation structure, characterized by significantly positive long-range correlations, in the inferior convexity of the macaque prefrontal cortex. This functional connectivity kernel was more pronounced during wakefulness than anesthesia and could be largely attributed to the spati

SUBMITTER: Safavi S 

PROVIDER: S-EPMC5899496 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature