Comparative analysis of core genome MLST and SNP typing within a European Salmonella serovar Enteritidis outbreak.

ABSTRACT: Multi-country outbreaks of foodborne bacterial disease present challenges in their detection, tracking, and notification. As food is increasingly distributed across borders, such outbreaks are becoming more common. This increases the need for high-resolution, accessible, and replicable isolate typing schemes. Here we evaluate a core genome multilocus typing (cgMLST) scheme for the high-resolution reproducible typing of Salmonella enterica (S. enterica) isolates, by its application to a large European outbreak of S. enterica serovar Enteritidis. This outbreak had been extensively characterised using single nucleotide polymorphism (SNP)-based approaches. The cgMLST analysis was congruent with the original SNP-based analysis, the epidemiological data, and whole genome MLST (wgMLST) analysis.

SUBMITTER: Pearce ME 

PROVIDER: S-EPMC5899760 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature