Synthesis of stable polymetalated aromatic complexes through metal-macrocycle capsule-triggered cyclization.

ABSTRACT: Polymetalated aromatic compounds are of great interest because of their intermediate roles in many organic transformations. However, they are elusive and synthetically challenging. In this study, a dynamic coordination capsule constructed by a flexible macrocycle and silver(i) ions is applied to trigger one-step or cascade cyclization reactions for various alkyne substrates, finally leading to five unprecedented polysilver heteroaromatic intermediates (including indole, quinoline, benzocarbazole and 2,2'-biindole). The acquired heteroaromatic species is doubly charged, particularly at vicinal positions, and each is surrounded by a tetrasilver aggregate. The metal-macrocycle capsule holds a great potential of flexibly adjusting its conformation to adapt different polysilver heteroaromatic s

SUBMITTER: He X 

PROVIDER: S-EPMC5900432 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature