Modified dixon-based renal dynamic contrast-enhanced MRI facilitates automated registration and perfusion analysis.

ABSTRACT:

Purpose

Renal dynamic contrast-enhanced (DCE) MRI provides information on renal perfusion and filtration. However, clinical implementation is hampered by challenges in postprocessing as a result of misalignment of the kidneys due to respiration. We propose to perform automated image registration using the fat-only images derived from a modified Dixon reconstruction of a dual-echo acquisition because these provide consistent contrast over the dynamic series.

Methods

DCE data of 10 hypertensive patients was used. Dual-echo images were acquired at 1.5 T with temporal resolution of 3.9 s during contrast agent injection. Dixon fat, water, and in-phase and opposed-phase (OP) images were reconstructed. Postprocessing was automated. Registration was performed both to fat images and

SUBMITTER: de Boer A 

PROVIDER: S-EPMC5900902 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature