Landscape attributes governing local transmission of an endemic zoonosis: Rabies virus in domestic dogs.

ABSTRACT: Landscape heterogeneity plays an important role in disease spread and persistence, but quantifying landscape influences and their scale dependence is challenging. Studies have focused on how environmental features or global transport networks influence pathogen invasion and spread, but their influence on local transmission dynamics that underpin the persistence of endemic diseases remains unexplored. Bayesian phylogeographic frameworks that incorporate spatial heterogeneities are promising tools for analysing linked epidemiological, environmental and genetic data. Here, we extend these methodological approaches to decipher the relative contribution and scale-dependent effects of landscape influences on the transmission of endemic rabies virus in Serengeti district, Tanzania (area ~4,900 km

SUBMITTER: Brunker K 

PROVIDER: S-EPMC5900915 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature