Pain and Kidney Function Decline and Mortality: A Cohort Study of US Veterans.

ABSTRACT:

Background

Chronic pain is a common condition in the general population. However, large epidemiologic studies examining the role of pain in the deterioration of kidney function, development of chronic kidney disease, and risk for death are lacking.

Study design

Retrospective cohort study.

Setting & participants

A nationally representative cohort of 2,360,056 US veterans with baseline estimated glomerular filtration rates (eGFRs) ≥ 60mL/min/1.73m(2), followed up from October 2004 to September 2006.

Predictor

4 pain categories were compared: none (score, 0), mild (1-4), moderate (5-6), or severe (≥7).

Outcomes

eGFR decline (determined by eGFR slope) and combined incident eGFR<60mL/min/1.73m(2) or all-cause death.

Measurements

We examined the pain ma

SUBMITTER: Ravel V 

PROVIDER: S-EPMC5901765 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature