Prognostic score to predict mortality during TB treatment in TB/HIV co-infected patients.

ABSTRACT:

Background

Estimating mortality risk during TB treatment in HIV co-infected patients is challenging for health professionals, especially in a low TB prevalence population, due to the lack of a standardized prognostic system. The current study aimed to develop and validate a simple mortality prognostic scoring system for TB/HIV co-infected patients.

Methods

Using data from the CDC's Tuberculosis Genotyping Information Management System of TB patients in Texas reported from 01/2010 through 12/2016, age ≥15 years, HIV(+), and outcome being "completed" or "died", we developed and internally validated a mortality prognostic score using multiple logistic regression. Model discrimination was determined by the area under the receiver operating characteristic (ROC) curve (AUC). The m

SUBMITTER: Nguyen DT 

PROVIDER: S-EPMC5901929 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature