Time rescaling reproduces EEG behavior during transition from propofol anesthesia-induced unconsciousness to consciousness.

ABSTRACT: General anesthesia (GA) is a reversible manipulation of consciousness whose mechanism is mysterious at the level of neural networks leaving space for several competing hypotheses. We recorded electrocorticography (ECoG) signals in patients who underwent intracranial monitoring during awake surgery for the treatment of cerebral tumors in functional areas of the brain. Therefore, we recorded the transition from unconsciousness to consciousness directly on the brain surface. Using frequency resolved interferometry; we studied the intermediate ECoG frequencies (4-40 Hz). In the theoretical study, we used a computational Jansen and Rit neuron model to simulate recovery of consciousness (ROC). During ROC, we found that f increased by a factor equal to 1.62 ± 0.09, and δf varied by the same facto

SUBMITTER: Boussen S 

PROVIDER: S-EPMC5902625 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature