Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate.

ABSTRACT:

Background

Pregnant women with systemic lupus erythematosus (SLE) have increased risk of adverse outcomes including disease flare, spontaneous abortion, preeclampsia/eclampsia, premature birth and maternal death. However, pregnancy outcomes among adolescents and young women with SLE have not been well-explored. Our objective was to compare risk of adverse pregnancy outcomes in adolescents and young women with SLE to risk among peers without SLE.

Methods

We studied the 2000-2011 Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) to estimate the prevalence of adverse pregnancy outcomes in women with SLE aged ≤ 21 years at time of delivery. Outcomes were compared to peers without SLE by using multivariate logistic regression to calculate odd

SUBMITTER: Ling N 

PROVIDER: S-EPMC5902884 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature