Incidence and risk factors for recurrent Henoch-Schonlein purpura in children from a 16-year nationwide database.

ABSTRACT:

Background

The recurrence rate of Henoch-Schönlein purpura (HSP) is 2.7%-30%, with varied average intervals between the first and second episodes. Few studies have explored the incidence and risk factors for recurrent HSP.

Methods

We used a 16-year nationwide database to analyze the incidence of recurrent HSP. Patients with HSP were identified, and risk factors for recurrent HSP were explored. Kaplan-Meier and Cox regression model analyses were performed, and covariates were adjusted in the multivariate model.

Results

From January 1, 1997 to December 31, 2012, among 2,886,836 individuals in the National Health Insurance Research Database, 1002 HSP patients aged < 18 years were identified. Among them, 164 had ≥2 HSP episodes (recurrence rate, 16.4%; incidence of recurr

SUBMITTER: Lei WT 

PROVIDER: S-EPMC5902957 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature