A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei.

ABSTRACT: Recent advances in magnetic resonance imaging methods, including data acquisition, pre-processing and analysis, have benefited research on the contributions of subcortical brain nuclei to human cognition and behavior. At the same time, these developments have led to an increasing need for a high-resolution probabilistic in vivo anatomical atlas of subcortical nuclei. In order to address this need, we constructed high spatial resolution, three-dimensional templates, using high-accuracy diffeomorphic registration of T1- and T2- weighted structural images from 168 typical adults between 22 and 35 years old. In these templates, many tissue boundaries are clearly visible, which would otherwise be impossible to delineate in data from individual studies. The resulting delineations of subcortical

SUBMITTER: Pauli WM 

PROVIDER: S-EPMC5903366 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature