Domain-general subregions of the medial prefrontal cortex contribute to recovery of language after stroke.

ABSTRACT: We hypothesized that the recovery of speech production after left hemisphere stroke not only depends on the integrity of language-specialized brain systems, but also on 'domain-general' brain systems that have much broader functional roles. The presupplementary motor area/dorsal anterior cingulate forms part of the cingular-opercular network, which has a broad role in cognition and learning. Consequently, we have previously suggested that variability in the recovery of speech production after aphasic stroke may relate in part to differences in patients' abilities to engage this domain-general brain region. To test our hypothesis, 27 patients (aged 59 ± 11 years) with a left hemisphere stroke performed behavioural assessments and event-related functional magnetic resonance imaging tasks at

SUBMITTER: Geranmayeh F 

PROVIDER: S-EPMC5903407 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature