Structural Covariance Networks in Children with Autism or ADHD.

ABSTRACT:

Background

While autism and attention-deficit/hyperactivity disorder (ADHD) are considered distinct conditions from a diagnostic perspective, clinically they share some phenotypic features and have high comorbidity. Regardless, most studies have focused on only one condition, with considerable heterogeneity in their results. Taking a dual-condition approach might help elucidate shared and distinct neural characteristics.

Method

Graph theory was used to analyse topological properties of structural covariance networks across both conditions and relative to a neurotypical (NT; n = 87) group using data from the ABIDE (autism; n = 62) and ADHD-200 datasets (ADHD; n = 69). Regional cortical thickness was used to construct the structural covariance networks. This was analysed in a

SUBMITTER: Bethlehem RAI 

PROVIDER: S-EPMC5903412 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature