Is periodontitis a risk indicator for cancer? A meta-analysis.

ABSTRACT:

Background

The aim of the present systematic review was to evaluate the hypothesis of an association between periodontitis and the development of cancer.

Methods

Two reviewers independently screened electronic and manual sources for pertinent articles. Primary outcome measures were the occurrence of neoplasm diagnosis in exposed and non-exposed groups, reported to evaluate association between cancer and periodontitis.

Results

Of the 490 initially retrieved papers 10 were included in the qualitative synthesis and eight in the quantitative synthesis; the eight papers covered six studies. Considering hazard ratios, a statistically significant association was found for all cancers studied (1.14; CI 95%: 1.04, 1.24), digestive tract cancer (1.34; CI 95%: 1.05, 1.72), pancr

SUBMITTER: Corbella S 

PROVIDER: S-EPMC5903629 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature