Growth trajectories and oxygen use in neuroendocrine cell hyperplasia of infancy.

ABSTRACT: RATIONALE:Neuroendocrine cell hyperplasia of infancy (NEHI) typically presents in infancy with tachypnea, retractions, and hypoxemia. Some infants have failure to thrive, yet the frequency of this and other non-respiratory phenotypic features have not been delineated. While gradual improvement occurs, the clinical course is variable and the duration of supplemental oxygen requirement has not been defined. OBJECTIVES:Our objective was to identify factors in NEHI that may drive differences in clinical course. We hypothesized that failure to thrive would be associated with greater duration of supplemental oxygen use. METHODS:Children with NEHI were identified as a nested retrospective cohort within an ongoing observational prospective study. An electronic questionnaire evaluating health statu

SUBMITTER: Nevel RJ 

PROVIDER: S-EPMC5903936 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature