PyMUS: Python-Based Simulation Software for Virtual Experiments on Motor Unit System.

ABSTRACT: We constructed a physiologically plausible computationally efficient model of a motor unit and developed simulation software that allows for integrative investigations of the input-output processing in the motor unit system. The model motor unit was first built by coupling the motoneuron model and muscle unit model to a simplified axon model. To build the motoneuron model, we used a recently reported two-compartment modeling approach that accurately captures the key cell-type-related electrical properties under both passive conditions (somatic input resistance, membrane time constant, and signal attenuation properties between the soma and the dendrites) and active conditions (rheobase current and afterhyperpolarization duration at the soma and plateau behavior at the dendrites). To constru

SUBMITTER: Kim H 

PROVIDER: S-EPMC5904262 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature