Dynamic Neural State Identification in Deep Brain Local Field Potentials of Neuropathic Pain.

ABSTRACT: In neuropathic pain, the neurophysiological and neuropathological function of the ventro-posterolateral nucleus of the thalamus (VPL) and the periventricular gray/periaqueductal gray area (PVAG) involves multiple frequency oscillations. Moreover, oscillations related to pain perception and modulation change dynamically over time. Fluctuations in these neural oscillations reflect the dynamic neural states of the nucleus. In this study, an approach to classifying the synchronization level was developed to dynamically identify the neural states. An oscillation extraction model based on windowed wavelet packet transform was designed to characterize the activity level of oscillations. The wavelet packet coefficients sparsely represented the activity level of theta and alpha oscillations in loca

SUBMITTER: Luo H 

PROVIDER: S-EPMC5904287 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature