REDIdb 3.0: A Comprehensive Collection of RNA Editing Events in Plant Organellar Genomes.

ABSTRACT: RNA editing is an important epigenetic mechanism by which genome-encoded transcripts are modified by substitutions, insertions and/or deletions. It was first discovered in kinetoplastid protozoa followed by its reporting in a wide range of organisms. In plants, RNA editing occurs mostly by cytidine (C) to uridine (U) conversion in translated regions of organelle mRNAs and tends to modify affected codons restoring evolutionary conserved aminoacid residues. RNA editing has also been described in non-protein coding regions such as group II introns and structural RNAs. Despite its impact on organellar transcriptome and proteome complexity, current primary databases still do not provide a specific field for RNA editing events. To overcome these limitations, we developed REDIdb a specialized dat

SUBMITTER: Lo Giudice C 

PROVIDER: S-EPMC5904370 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature