Circulating Spexin Levels Negatively Correlate With Age, BMI, Fasting Glucose, and Triglycerides in Healthy Adult Women.

ABSTRACT:

Context

Spexin is a newly identified neuropeptide that is involved in satiety control, glucose, and lipids metabolism. It has also been related to human diseases, such as obesity and type 2 diabetes. However, whether spexin changes with age or not is still unclear.

Objective

The aim of this study is to investigate the relationship between circulating spexin levels and age and to study their interaction effects on body mass index (BMI), fasting glucose, and -lipids.

Design and participants

This is a cross-sectional study, including 68 healthy adult women whose ages are in a wide range (minimum: 23; median: 38.5; maximum: 64).

Outcome measures

The serum spexin levels were measured by an enzyme-linked immunosorbent assay. Fasting glucose, total cholesterol, trigly

SUBMITTER: Lin CY 

PROVIDER: S-EPMC5905385 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature