The Evolutionary History of Nebraska Deer Mice: Local Adaptation in the Face of Strong Gene Flow.

ABSTRACT: The interplay of gene flow, genetic drift, and local selective pressure is a dynamic process that has been well studied from a theoretical perspective over the last century. Wright and Haldane laid the foundation for expectations under an island-continent model, demonstrating that an island-specific beneficial allele may be maintained locally if the selection coefficient is larger than the rate of migration of the ancestral allele from the continent. Subsequent extensions of this model have provided considerably more insight. Yet, connecting theoretical results with empirical data has proven challenging, owing to a lack of information on the relationship between genotype, phenotype, and fitness. Here, we examine the demographic and selective history of deer mice in and around the Nebraska

SUBMITTER: Pfeifer SP 

PROVIDER: S-EPMC5905656 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature