Quality of Randomized Controlled Trials Reporting in the Treatment of Adult Patients with High-Grade Gliomas.

ABSTRACT:

Background

The randomized controlled trial (RCT) is the gold standard to objectively assess the effect of treatments. To help improve the quality of RCTs, experts established a list of recommendations, the CONsolidated Standards of Reporting Trials (CONSORT) Statement. In this study, we evaluated the implementation of the CONSORT Statement in the field of high-grade gliomas in adult patients and looked for criteria associated with higher quality of RCTs.

Materials and methods

We searched all high-grade gliomas RCTs published in PubMed between January 1990 and December 2016. The quality of these RCTs was assessed by completing a modified CONSORT Score (CS).

Results

Ninety-six published RCTs were identified. The median CS was 19.5 on a scale of 0-33. Items were not equa

SUBMITTER: Tardy MP 

PROVIDER: S-EPMC5905683 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature