The CYP1A2 -163C>A polymorphism does not alter the effects of caffeine on basketball performance.

ABSTRACT:

Purpose

The aim of this investigation was to analyze the influence of the genetic variations of the -163C>A polymorphism of the CYP1A2 gene on the ergogenic effects of caffeine in elite basketball players.

Methods

Nineteen elite basketball players (10 men and 9 women) ingested 3 mg⋅kg-1 of caffeine or a placebo 60 min before performing 10 repetitions of the following series: the Abalakov jump test followed by the Change-of-Direction and Acceleration Test (CODAT). The players then competed in a 20-min simulated basketball game. Self-perceived performance and side effects were recorded by questionnaires after the trials. The effects of caffeine on basketball performance were established according to players' CYP1A2 genotype (rs762551): AA homozygotes (n = 10) and C-allele carr

SUBMITTER: Puente C 

PROVIDER: S-EPMC5905997 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature