The impact of passive case detection on the transmission dynamics of gambiense Human African Trypanosomiasis.

ABSTRACT: Gambiense Human African Trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease affecting largely rural populations in Western and Central Africa. The main method for detecting and treating cases of gambiense HAT are active screening through mobile teams and passive detection through self-referral of patients to dedicated treatment centres or hospitals. Strategies based on active case finding and treatment have drastically reduced the global incidence of the disease over recent decades. However, little is known about the coverage and transmission impact of passive case detection. We used a mathematical model to analyse data from the period between active screening sessions in hundreds of villages that were monitored as part of three HAT control projects run by Médecins Sans

SUBMITTER: Checchi F 

PROVIDER: S-EPMC5906023 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature