Cognitive mechanisms of inhibitory control deficits in autism spectrum disorder.

ABSTRACT:

Background

Inhibitory control deficits are common in autism spectrum disorder (ASD) and associated with more severe repetitive behaviors. Inhibitory control deficits may reflect slower execution of stopping processes, or a reduced ability to delay the onset of behavioral responses in contexts of uncertainty. Previous studies have documented relatively spared stopping processes in ASD, but whether inhibitory control deficits in ASD reflect failures to delay response onset has not been systematically assessed. Further, while improvements in stopping abilities and response slowing are seen through adolescence/early adulthood in health, their development in ASD is less clear.

Methods

A stop-signal test (SST) was administered to 121 individuals with ASD and 76 age and IQ-matched

SUBMITTER: Schmitt LM 

PROVIDER: S-EPMC5906199 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature