Novel naphthylpyridines from cobalt-catalyzed cyclotrimerization of a chiral diyne.

ABSTRACT:

Abstract

The concise synthesis of a novel chiral diyne substrate for the assembly of chiral naphthylpyridines was described and different conditions for the cobalt-catalyzed co-cyclotrimerization with nitriles investigated. The products are novel naphthylpyridines possessing configurationally stable biaryl axes.

Graphical abstract

SUBMITTER: Trommer V 

PROVIDER: S-EPMC5906485 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature