Prenatal exposure to methadone or buprenorphine: Early childhood developmental outcomes.

ABSTRACT:

Background

Methadone and buprenorphine are recommended to treat opioid use disorders during pregnancy. However, the literature on the relationship between longer-term effects of prenatal exposure to these medications and childhood development is both spare and inconsistent.

Methods

Participants were 96 children and their mothers who participated in MOTHER, a randomized controlled trial of opioid-agonist pharmacotherapy during pregnancy. The present study examined child growth parameters, cognition, language abilities, sensory processing, and temperament from 0 to 36 months of the child's life. Maternal perceptions of parenting stress, home environment, and addiction severity were also examined.

Results

Tests of mean differences between children prenatally exposed to m

SUBMITTER: Kaltenbach K 

PROVIDER: S-EPMC5906792 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature