Long-term prognostic implications of risk factors associated with tumor size: a case study of women regularly attending screening.

ABSTRACT: BACKGROUND:Breast cancer prognosis is strongly associated with tumor size at diagnosis. We aimed to identify factors associated with diagnosis of large (> 2 cm) compared to small tumors, and to examine implications for long-term prognosis. METHODS:We examined 2012 women with invasive breast cancer, of whom 1466 had screen-detected and 546 interval cancers that were incident between 2001 and 2008 in a population-based screening cohort, and followed them to 31 December 2015. Body mass index (BMI) was ascertained after diagnosis at the time of study enrollment during 2009. PD was measured based on the contralateral mammogram within 3 years before diagnosis. We used multiple logistic regression modeling to examine the association between tumor size and body mass index (BMI), mammographic perce

SUBMITTER: Strand F 

PROVIDER: S-EPMC5907386 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature