Relations of Sex to Diagnosis and Outcomes in Acute Coronary Syndrome.

ABSTRACT:

Background

The atypical presentation of women with acute coronary syndrome (ACS) has been related to delayed diagnosis and treatment, which may explain worse outcome compared with men.

Methods and results

We analyzed pooled data of 2520 patients of 2 prospective cohorts in terms of differences in presentation and management of women and men suggestive of ACS. Using logistic regression, we established 2 diagnostic models and tested their diagnostic performance in both sexes separately. Sex-specific differences in management of patients with ACS were ascertained and a 2-year follow-up was performed. Women were older than men (median 67 versus 61 years, P=0.001), had more often dyspnea (22% versus 18%, P=0.024), nausea or vomiting (26% versus 16%, P=0.001)

SUBMITTER: Sorensen NA 

PROVIDER: S-EPMC5907542 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature