Outpatient Parenteral Antimicrobial Therapy in Pediatric Medicaid Enrollees.

ABSTRACT:

Background

Outpatient parenteral antimicrobial therapy (OPAT) is overused in cases where highly bioavailable oral alternatives would be equally effective. However, the scope of OPAT use for children nationwide is poorly understood. Our objective was to characterize OPAT use and clinical outcomes for a large population of pediatric Medicaid enrollees treated with OPAT.

Methods

We analyzed the Truven MarketScan Medicaid claims database between 2009 and 2012. An OPAT episode was identified by capturing children with claims data indicating home infusion therapy for an intravenous antimicrobial. We characterized OPAT use by describing patient demographics, diagnoses, and antimicrobials prescribed. We categorized an antimicrobial as highly bioavailable if ≥80% systemic exposure wa

SUBMITTER: Goldman JL 

PROVIDER: S-EPMC5907854 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature