Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal.

ABSTRACT:

Background.

Pertussis is estimated to cause 2 percent of childhood deaths globally and is a growing public health problem in developed countries despite high vaccination coverage. Infants are at greatest risk of morbidity and mortality. Maternal vaccination during pregnancy may be effective to prevent pertussis in young infants, but population-based estimates of disease burden in infants are lacking, particularly in low-income countries. The objective of this study was to estimate the incidence of pertussis in infants less than 6 months of age in Sarlahi District, Nepal.

Methods.

Nested within a population-based randomized controlled trial of influenza vaccination during pregnancy, infants were visited weekly from birth through 6 months to assess respiratory illness in the p

SUBMITTER: Hughes MM 

PROVIDER: S-EPMC5907881 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature