Dataset Information
Retrospective Analysis of Candida-related Conditions in Infancy and Early Childhood Caries.
Ontology highlight
ABSTRACT: Purpose
The purpose of this study was to assess whether there is an association between oral thrush or other Candida-related conditions in infancy and early childhood caries (ECC) diagnosed by pediatricians.Methods
We conducted a retrospective cohort study using electronic health records from six national children's hospitals that participate in the PEDSnet research network. There were 1,012,668 children with a visit at ages one to 12 months and another visit at ages 13 to 71 months. The independent variables were diagnosis of thrush or Candida-related conditions in the first year of life, while the dependent variable was diagnosis of ECC between 13 to 71 months old.Results
Oral thrush detection was strongly associated with ECC, particularly between 13 and 36 months (rate ratio between 2.7 [95 percent confidence interval (95% CI) equals 2.5 to 2.9; P<.001] and 3.0 [95% CI, equals 2.8 to 3.4; P<.001]). A similar trend was observed with other Candida-related conditions.Conclusions
Oral thrush may be a risk factor for early childhood caries.
SUBMITTER: Jean J
PROVIDER: S-EPMC5907929 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
Retrospective Analysis of Candida-related Conditions in Infancy and Early Childhood Caries.
Pediatric dentistry 20180301 2
<h4>Purpose</h4>The purpose of this study was to assess whether there is an association between oral thrush or other Candida-related conditions in infancy and early childhood caries (ECC) diagnosed by pediatricians.<h4>Methods</h4>We conducted a retrospective cohort study using electronic health records from six national children's hospitals that participate in the PEDSnet research network. There were 1,012,668 children with a visit at ages one to 12 months and another visit at ages 13 to 71 mon ...[more]
