Odorant binding protein 69a connects social interaction to modulation of social responsiveness in Drosophila.

ABSTRACT: Living in a social environment requires the ability to respond to specific social stimuli and to incorporate information obtained from prior interactions into future ones. One of the mechanisms that facilitates social interaction is pheromone-based communication. In Drosophila melanogaster, the male-specific pheromone cis-vaccenyl acetate (cVA) elicits different responses in male and female flies, and functions to modulate behavior in a context and experience-dependent manner. Although it is the most studied pheromone in flies, the mechanisms that determine the complexity of the response, its intensity and final output with respect to social context, sex and prior interaction, are still not well understood. Here we explored the functional link between social interaction and pheromone-based

SUBMITTER: Bentzur A 

PROVIDER: S-EPMC5908198 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature