Incidence and risk factors for venous thromboembolism in patients with pretreated advanced pancreatic carcinoma.

ABSTRACT: Patients with pancreatic carcinoma are at an increased risk of venous thromboembolism (VTE), which is a major cause of morbidity and mortality in various types of cancer. The aim of this study was to determine the incidence and clinical significance of VTE in patients with pancreatic carcinoma, and to identify biomarkers for the detection of VTE in these patients. The eligibility criteria were chemo-naïve patients with primary pancreatic carcinoma, an Eastern Cooperative Oncology Group performance status of 0-2, and adequate organ function. All patients were screened for VTE using compression ultrasonography and dynamic computed tomography. The primary endpoint was the incidence of VTE, which we hypothesized would be between 10.0-20.0% for symptomatic and asymptomatic patients combined. As

SUBMITTER: Kondo S 

PROVIDER: S-EPMC5908292 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature