Associations between serum vitamin D and the risk of female reproductive tumors: A meta-analysis with trial sequential analysis.

ABSTRACT:

Background

Female reproductive tumors are common with high morbidity and mortality worldwide; however, the association between gynecological tumors and serum vitamin D is controversial. The aim of this meta-analysis was to evaluate the relationship between insufficiency of serum vitamin D and the occurrence of benign and malignant gynecological tumors.

Methods

Studies from inception to June 2017 were searched in the electronic databases: National Library of Medicine (PubMed), Web of Science (Clerivate), and Cochrane Database of Systematic Reviews (Cochrane Library, CDSR) by 2 investigators independently. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model. STATA 12.0 Software and Trial Sequential Analysis (TSA) software were app

SUBMITTER: Yan L 

PROVIDER: S-EPMC5908580 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature