The neural determinants of age-related changes in fluid intelligence: a pre-registered, longitudinal analysis in UK Biobank.

ABSTRACT: Background: Fluid intelligence declines with advancing age, starting in early adulthood. Within-subject declines in fluid intelligence are highly correlated with contemporaneous declines in the ability to live and function independently. To support healthy aging, the mechanisms underlying these declines need to be better understood. Methods: In this pre-registered analysis, we applied latent growth curve modelling to investigate the neural determinants of longitudinal changes in fluid intelligence across three time points in 185,317 individuals (N=9,719 two waves, N=870 three waves) from the UK Biobank (age range: 39-73 years). Results: We found a weak but significant effect of cross-sectional age on the mean fluid intelligence score, such that older individuals scored

SUBMITTER: Kievit RA 

PROVIDER: S-EPMC5909055 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature