Ontology highlight
ABSTRACT:
SUBMITTER: Carrejo NC
PROVIDER: S-EPMC5909404 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
ACS biomaterials science & engineering 20180316 4
In vivo, multidomain peptide (MDP) hydrogels undergo rapid cell infiltration and elicit a mild inflammatory response which promotes angiogenesis. Over time, the nanofibers are degraded and a natural collagen-based extracellular matrix is produced remodeling the artificial material into natural tissue. These properties make MDPs particularly well suited for applications in regeneration. In this work, we test the regenerative potential of MDP hydrogels in a diabetic wound healing model. When appli ...[more]