Evaluation of the added value of ¹H-magnetic resonance spectroscopy for the diagnosis of pediatric brain lesions in clinical practice.

ABSTRACT:

Background

Magnetic resonance spectroscopy (MRS) aids noninvasive diagnosis of pediatric brain tumors, but use in clinical practice is not well documented. We aimed to review clinical use of MRS, establish added value in noninvasive diagnosis, and investigate potential impact on patient care.

Methods

Sixty-nine children with lesions imaged using MRS and reviewed by the tumor board from 2014 to 2016 met inclusion criteria. Contemporaneous MRI diagnosis, spectroscopy analysis, histopathology, and clinical information were reviewed. Final diagnosis was agreed on by the tumor board at study end.

Results

Five cases were excluded for lack of documented MRI diagnosis. The principal MRI diagnosis by pediatric radiologists was correct in 59%, increasing to 73% with addition of

SUBMITTER: Manias K 

PROVIDER: S-EPMC5909808 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature