The association between an inflammatory diet and global cognitive function and incident dementia in older women: The Women's Health Initiative Memory Study.

ABSTRACT: INTRODUCTION:The Mediterranean and Dietary Approaches to Stop Hypertension diets have been associated with lower dementia risk. We evaluated dietary inflammatory potential in relation to mild cognitive impairment (MCI)/dementia risk. METHODS:Baseline food frequency questionnaires from n = 7085 women (aged 65-79 years) were used to calculate Dietary Inflammatory Index (DII) scores that were categorized into four groups. Cognitive function was evaluated annually, and MCI and all-cause dementia cases were adjudicated centrally. Mixed effect models evaluated cognitive decline on over time; Cox models evaluated the risk of MCI or dementia across DII groups. RESULTS:Over an average of 9.7 years, there were 1081 incident cases of cognitive impairment. Higher DII scores were associated with greate

SUBMITTER: Hayden KM 

PROVIDER: S-EPMC5909961 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature