ClustAGE: a tool for clustering and distribution analysis of bacterial accessory genomic elements.

ABSTRACT:

Background

The non-conserved accessory genome of bacteria can be associated with important adaptive characteristics that can contribute to niche specificity or pathogenicity of strains. High degrees of structural and compositional diversity in genomic islands and other elements of the accessory genome can complicate characterization of accessory genome contents among populations of strains. Methods for easily and effectively defining the distributions of discrete elements of the accessory genome among bacterial strains in a population are needed to explore the relationships between the flexible genome and bacterial adaptive traits.

Results

We have developed the open-source software package ClustAGE. This program, written in Perl, uses BLAST to cluster nucleotide accessory ge

SUBMITTER: Ozer EA 

PROVIDER: S-EPMC5910555 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature